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Tirzepatide was the most effective GLP-1RA drug on glycaemic control by reducing HbA 1c and fasting blood glucose

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doi: 10.1210/jcemcr/luac017 [DOI] [PMC free article] [PubMed] [Google Scholar] 47

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Clinical implication Considering the potential for gastric food retention and aspiration risks associated with surgical or endoscopic interventions, the American Society of Anesthesiologists recommends the discontinuation of short-acting GLP-1 RAs one day and long-acting formulations at least 1 week before surgical procedures [27]

When that microbial ecosystem is out of balance, the signal weakens
