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Losing too much muscle while taking a GLP-1 medication can result in decreased strength, slower metabolism, increased risk of falls, and a higher likelihood of regaining weight once you stop taking the medication

Beyond their effects on glycemic control and weight loss, GLP-1 RAs are now being evaluated for a range of other conditions, including cardiovascular disease, chronic kidney disease, metabolic dysfunction-associated steatotic liver disease, obstructive sleep apnea, knee osteoarthritis, polycystic ovary syndrome, neurodegenerative disease, and substance abuse disorders

Clothes fit differently, energy shifts, and the scale finally feels like its cooperating

Such strategies should be based on reinforcing persistence and adherence to the prescribed treatment and reducing therapeutic inertia

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Patients should be aware that tirzepatide can reduce the effectiveness of oral contraceptives, particularly after starting treatment or increasing doses