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That rate was much higher than among patients using the medications for Type 2 diabetes, which makes sense: Diabetes is widely understood as a chronic condition, while many people still approach weight loss medication as something temporary

Its mechanism involves enhancing insulin secretion, suppressing glucagon, and slowing gastric emptying, all contributing to a prolonged feeling of fullness

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Especially when you are committing to a medication you may take for months or years

, Mergler, B

"I'm not going to, but I could weep right now for all of the many days and nights I've journaled about this being my fault and why can't I conquer this thing?" Winfrey told host Jane Pauley