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These are ceiling doses, not targets

In the periphery, posttranslational processing of preproglucagon in the alpha-cells of the pancreas produces glucagon and a small amount of GLP-1 whereas the main source of peripheral GLP-1 production occurs through the posttranslational processing of preproglucagon in the L-cells of the gut (reviewed in Holst, 2007 and Campbell and Drucker, 1992

The abstract (but not the complete study) for the SURMOUNT-OSA trial was just published in the New England Journal of Medicine

Yangzhou: Yangzhou University