is glp 1 dangerous to take GLP-1 Medications for Weight Loss: Semaglutide vs Tirzepatide vs Retat – Revolution Health & Wellness Researchers find GLP-1 medications safe

While injection-site irritation is well recognized, clinicians are increasingly observing broader skin changes in patients treated with semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)

Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

GLP-1 medications consistently raise HDL levels by 310% in clinical populations, an effect driven by improved insulin sensitivity and reduced systemic inflammation

Malhotra A, Grunstein RR, Fietze I, Weaver TE, Redline S, Azarbarzin A, et al

doi: 10.1210/endo.135.5.7956929

This metabolite, known as 5-HIAA is excreted via the urine once it has undergone phase-2 glucaronidation or sulfation (see reference 5 for more detail)