safety of glp 1 receptor agonists Efficacy and LY3298176, a novel dual GIP and GLP-1 agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial GLP-1 receptor agonists are transforming

Understanding peptide receptor pharmacology clarifies how these seemingly contradictory effects balance in practice

E.DierckxR

Glucagon-like peptide 1 induces pancreatic -cell proliferation via transactivation of the epidermal growth factor receptor

Direct intraparenchymal delivery of low, ventricle subthreshold doses of GLP1R agonists to GLP1R expressing nuclei throughout the brain, including e.g., NTS, lPBN, ventral tegmental area (VTA), PVH, PVT, nucleus accumbens (NAcc), ventral hippocampus, and lateral septum reduced food intake via reductions in meal size

10.1007/s00125-007-0706-0 Diabetologia 15 ChenS.YinL.XuZ.AnF.LiuA.WangY.et al (2016)

Cold foods often cause less nausea than hot foods