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Needle length and gauge should be chosen with a clinician or pharmacist, especially for children, people with low body fat, pregnancy, dexterity concerns, or prior injection pain

Example code lists used to identify covariates are included in supplementary table S2

GLP-1R immunoreactivity has also been detected in mouse cartilage and synovium using immunofluorescence techniques

These strategies involve the use of either DPP4-resistant synthetic analogues of GLP-1 (termed GLP-1 mimetics) or DPP4 inhibitors

Unlike some life-sustaining medications, there's a substantial gap between the eligible population for GLP-1s and those actually on therapy

The success of GLP-1R-targeting drugs highlights their viability as a treatment approach