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Accessed 16 July 2021 158.Diabetes UK (2021) Diabetes when youre unwell

The three-way comparison guide provides detailed efficacy and mechanism analysis

The robust reduction in HbA1c (0.5% to 1.5%) is anchored in the PKA-mediated sensitization of the -cell, a mechanism that remains glucose-dependent and thus carries a low risk of hypoglycemia (Alharbi, 2025)

73 The phase 2 LixiPark trial showed that lixisenatide, a GLP-1 receptor agonist with measurable brain penetration, slowed motor progression in early Parkinsons disease compared with placebo

pp 1026 Buchman AL, Katz S, Fang JC, Bernstein CN, Abou-Assi SG (2010) Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohns disease