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In the microglia, fibrillar -synuclein activates the NF-B pathway (Kam et al., 2020), central to the inflammatory microglial response

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529 In a UC mouse model, astragalus polysaccharides similarly regulate the levels of inflammatory factors and oxidative stress to alleviate the inflammatory response and oxidative stress in mice, maintain the integrity of the intestinal mucosal barrier, and alleviate intestinal tissue damage