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The widespread off-label use of ADM semaglutide (Ozempic) and tirzepatide (Mounjaro) by patients without T2D allowed Truveta Research to study comparative outcomes for a large, real-world population before clinical trials results in a similar population were available

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The subgroup treated with the maximum dose of tirzepatide lost an average of 22.5% of their body weight (approximately 24 kg) and 63% of subjects lost at least 20% of their body weight