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In the prescribing information, the tablet dosing schedule steps up from 1.5 mg 4 mg 9 mg 25 mg over time to help tolerability
Retatrutide is often referred to as a triple-agonist metabolic therapy because it activates three key metabolic hormones at once: GLP-1 GIP Glucagon This triple mechanism may produce stronger metabolic effects than current medications like Mounjaro, Ozempic, or Semaglutide
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Grade A = Clear evidence from well-conducted, generalizable randomized controlled trials that are adequately powered
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2024 surveillance of non-alcoholic fatty liver disease (NAFLD): assessment and management (NG49)
