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Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer

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It showed that patients taking metformin did experience some weight loss (around 1-2 pounds which I find to be accurate nowadays)

The peptide stacking guide covers general principles of combining multiple compounds
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This is the most popular split dosing schedule and likely the best compromise between side effect reduction and efficacy preservation

Changes to background glucose-lowering medications that occurred after randomisation and lasted more than 2 weeks are summarised in ESM Table 5
