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Despite lower efficacy and tolerability shown by nasally administered PYY agonists in early studies, long-acting subcutaneous PYY receptor agonists such as PYY 1875 are undergoing early-phase clinical trials to evaluate their safety and effectiveness as monotherapy or in combination with GLP-1 receptor agonists for the treatment of obesity
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Efforts must also focus on preventing and treating infection-related cancers, while increasing investment in cancer surgery and radiotherapycritical components in the curative treatment of many solid tumors (63)(64)
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The main differences are the absolute dose numbers and the number of intermediate steps
Staying hydrated is crucial, especially as dehydration can exacerbate side effects including headaches
