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Abstract Tirzepatide, a dual agonist for glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, has shown robust efficacy in treating diabetes and obesity, and in obese patients with heart failure with preserved ejection fraction (HFpEF), it reduced weight, lowered blood pressure, and improved outcomes

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Moreover, administration of exendin-4 led to a reduction in 5-HT and 5-HIAA, whereas GLP-1R antagonists increased the levels of serotonin and its metabolites [56]

Chromium: Chromium is a trace mineral with a recognized role in normal macronutrient metabolism

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Day 1 Breakfast: Coconut Chia Pudding with Berries Lunch: Turkey Zucchini Skillet Snack: Sunflower seed butter + cucumber slices Dinner: Garlic-Lime Shrimp with Cauliflower Rice Day 2 Breakfast: Creamy Avocado Smoothie (with plant protein powder) Lunch: Grilled Chicken & Cucumber Dill Salad Snack: Coconut yogurt with cinnamon + flaxseed Dinner: Slow-Roasted Chicken Thighs with Zucchini and Peppers Day 3 Breakfast: No-Oat NOats Hot Cereal with berries Lunch: Tuna Salad-Stuffed Avocado Snack: Roasted pumpkin seeds + seaweed snacks Dinner: Seared Pork Chop with Garlic Green Beans Day 4 Breakfast: Coconut Chia Pudding with raspberries Lunch: Turkey Lettuce Wraps with avocado mayo Snack: Protein smoothie popsicle (avocado + coconut milk + cinnamon) Dinner: Roasted Salmon with Steamed Broccoli Day 5 Breakfast: Savory Avocado Boats with turkey bacon Lunch: Leftover salmon salad over romaine with olive oil Snack: Chia pudding or sugar-free collagen hot cocoa Dinner: Beef Stir-Fry with Cauliflower Rice Day 6 Breakfast: Smoothie with coconut milk, spinach, berries, and chia seeds Lunch: Big Mac-Inspired Salad (no cheese) with ground turkey or beef Snack: Sunflower seeds or a small turkey wrap in romaine Dinner: Crispy Salmon Cakes with Cucumber Salad Day 7 Breakfast: No-Oat Hot Cereal with hemp hearts + blueberries Lunch: Chicken Thigh & Avocado Plate Snack: Coconut yogurt + cinnamon + cacao nibs Dinner: Bacon-Wrapped Pimento-Stuffed Peppers (dairy-free option) Grocery Tip: Shop from your protein staples first, then pick 23 veggies and a healthy fat to rotate through the week