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In: Standards of Medical Care in Diabetes2016

The NNTs for SGLT-2 inhibitors to reduce mortality are truly impressive, although 1 in 7 patients will get an additional genital infection in five years

Moreover, in the AMPLITUDE-O, HARMONY OUTCOMES and SUSTAIN-6 trials [50,56,59], there were significant reductions in the expanded composite outcome, defined as hospitalisations for unstable angina and urgent coronary revascularisations

Researchers now understand that GLP-1 operates as a metabolic hormone while also serving as an anti-inflammatory agent that functions within synovial spaces

The expression of Gcg in the pancreas, intestine, and brain is under the control of a single promoter and is initiated from an identical transcription start codon (Figure 2)

The initial recommended dosage of lixisenatide is 10 mcg once daily for at least 14 days