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As a result, increased obesity, insulin resistance (IR), type 2 diabetes mellitus (T2DM), and lipid metabolism changes have been linked to air pollution, exposure to chemical substances that interfere with metabolism, excessive consumption of ultra-processed foods, changes in the intestinal microbiota, and sedentary lifestyle

The microtubule-associated protein tau gene ( MAPT ), although primarily linked to neurological disorders, is also under investigation in oncology through the tau aggregation inhibitor LAM-226 , currently in active preclinical development, suggesting an alternative mechanistic direction for therapeutic exploration

Beyond quantitative preservation, maintaining skeletal muscle function, including strength and metabolic capacity, remains a critical therapeutic goal in ensuring long-term health outcomes

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Powders Maintain Leading Position Among Dosage Forms Powdered supplements accounted for 34.2% of the dosage form segment in 2024 and are forecast to reach 38% in 2025

For the last 50 years, bariatric surgery has been the most effective treatment for obesity resulting in approximately 25% weight loss, whilst also improving the control of type 2 diabetes mellitus (T2DM) and reducing cardiovascular and cancer deaths