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I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance)

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In 2024, we also saw unprecedented willingness by large numbers of patients to pay out of pocket, even in European markets, as public coverage of AOMs is still limited, at best, and more often non-existent

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This process preserves the full molecular spectrum of saffron, including volatile compounds like safranal, which are often lost during conventional extraction methods.Its content is 10 times higher in safranal and 20 times more concentrated in crocins than standard extracts, enhancing the effects of saffron on emotional balance

In this attempt, observational and experimental studies and review articles will be gathered from leading scientists in the field of diabetes mellitus.Areas to be covered in this Research Topic may include, but are not limited to:- Studies on the effect of SGLT2 inhibitors or GLP-1 receptor agonists on testosterone and gonadotropins in male patients with diabetes mellitus and hypogonadism- Studies on the effect of SGLT2 inhibitors or GLP-1 receptor agonists on testosterone gonadotropins in female patients with diabetes mellitus and p...