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Obesity creates similar frustrations

Limiting therapy duration: 63% are placing caps on how long a member can use the medication

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Additionally, patients receiving GLP-1 medications often have metabolic conditions that independently affect cancer risk, making it challenging to isolate drug effects

Timing matters during dose escalation: weeks 14 of tirzepatide treatment, when side effects peak, are poor windows for starting or intensifying intermittent fasting

Other side effects include fatigue, injection site reactions, and modest increases in heart rate