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Additionally, a new GLP-1 candidate, pemvidutide, has recently shown weight reductions in a Phase 2 trial with a lower percentage of muscle loss compared to other GLP-1s

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doi: 10.1016/b978-0-12-394440-5.00005-x

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This occurs because caloric restriction and rapid weight loss can trigger the body to break down muscle tissue for energy

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There is only limited data on the role of specific bacterial species on incretins

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