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By uniquely targeting GIP, GLP-1, and Glucagon receptors simultaneously, it shatters the efficacy limits of previous dual-agonists

Reddy's submission on April 28, 2026, describing it as the first generic semaglutide authorized by Health Canada and the first to be approved in the G7 [Source: canada.ca/en/health-canada/news/2026/04/canada-becomes-the-first-g7-country-to-approve-a-generic-version-of-semaglutide.html]

They lower blood sugar after meals, slow how fast the stomach empties, and act on appetite centres in the brain which is why they reduce hunger and are now licensed for weight loss as well as type 2 diabetes

Its like having a personal portion control coach built right into your system

Semaglutide works by acting like a hormone called glucagon-like peptide-1 (GLP-1), which promotes insulin production and also stimulates part of the brain that controls appetite

Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work