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The mechanism of GLP-1 agonists involves slowing gastric emptying, which prolongs the feeling of fullness after eating and, in turn, tends to reduce the frequency of eating
[cited 2025 Jul 27]

DPP-4 inhibitors are similarly effective as sulfonylureas in improving glucose control and are equivalent to metformin or even pioglitazone, especially in those who have not been taking diabetes medications previously [7]
doi: 10.1186/s12894-022-01017-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 8.Eisner BH, Eisenberg ML, Stoller ML

High Potency Antagonists of the Pancreatic Glucagon-like Peptide-1 Receptor
