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3.1.1 Lactobacillus acidophilus A leading probiotic validated for its ability to reduce cholesterol by over 50% in vitro , making it a valuable adjunct for cardiovascular wellness (72)

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Inhibiting PFKFB3 attenuates TGF-1 + IL-1-stimulated NLRP3 inflammasome activation and fibroblast activation The effects of PFKFB3-driven glycolysis on NLRP3 inflammasome activation in fibroblasts under the stress of TGF-1 + IL-1 were investigated by using 3PO, a selective PFKFB3 inhibitor

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