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However, adherence to such programs is often limited, with high attrition rates which are attributed to factors such as unrealistic expectations regarding the magnitude and timing of weight loss, the substantial time commitment required, and financial or logistical barriers to sustained participation [9,10]

Ahead of print

Losing weight more gradually, keeping up protein and strength training, and staying well hydrated all reduce how noticeable it becomes

10.1371/journal.ppat.1007581 27 FoleyS

Metformin belongs to the biguanides drug class

It focuses on improving visible firmness, supporting collagen organisation, enhancing oxygen utilisation at a cellular level, and reinforcing the skin barrier when skin feels depleted or fragile