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An earlier 2020 meta-analysis of 12 trials including 849 subjects found no significant reduction in body weight or BMI from berberine or barberry, although waist-to-hip ratio improved

Uncertain impact for Medicaid Medicaid is a state-federal program for low-income people

"It is intuitive that weight reduction in persons with obesity would have biomechanical benefits, such as reduced stress on the knee and other weight-bearing joints," he noted

Acute kidney injury: Sudden kidney failure, particularly in patients who become dehydrated from gastrointestinal side effects

Williams DL, Baskin DG, Schwartz MW

Practical considerations such as injection frequency, needle size, and gastrointestinal tolerability may also influence individual patient selection