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Endogenous GLP-1 alters postprandial functional connectivity between homeostatic and reward-related brain regions involved in regulation of appetite in healthy lean males: A pilotstudy

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These are different treatments with different contraindications and should not be compared as equivalent to GLP-1 medication

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The choice between metformin and GLP-1s, or any other blood sugar lowering medication, should be made based on individual factors, including the patient's medical history, lifestyle, treatment goals, and potential side effects

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