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Benefits of Weight Loss for the Heart Reduced strain on the heart muscle Lower systolic and diastolic blood pressure Improved cholesterol profiles (increased HDL, decreased LDL and triglycerides) Reduced risk of heart disease and stroke How GLP-1 Medications Support More Than Weight Loss GLP-1 receptor agonists such as semaglutide and tirzepatide were originally developed to support blood sugar control

However, if you increase your dose rapidly, side effects may return temporarily

These drugs also have a tumor risk black box warning as they can possibly cause thyroid tumors

Trulicity may worsen these conditions

Seek medical advice promptly if these symptoms develop

This combination is often used when a patient experiences food noise or cravings that a GLP-1 medication alone cannot fully quiet