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These decisions will centre on positioning new entrants, whether off-patent semaglutide or next-generation obesity medicines, in an increasingly crowded field

Preclinical data supports this framing: Konanur et al

Wegovy and Ozempic Health Concerns Wegovy (semaglutide) is a higher dose version of the blockbuster drug Ozempic, which was initially approved for the treatment of people with Type 2 diabetes, and is part of a popular new class of medications known as glucagon-like peptide-1 receptor agonists (GLP-1RAs)

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Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice

Semaglutide and levothyroxine Semaglutide was actually the subject of the formal pharmacokinetic study that quantified the 33% increase in levothyroxine exposure