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(Tirzepatide was approved without this data, but retatrutide's glucagon component might trigger additional scrutiny.) How to access retatrutide now (before commercial launch) While retatrutide isn't commercially available, people are using it today through three main pathways

No clinical trials have been completed in humans to date [8]

The contribution of psychiatric AEs in GLP-1 RAs is not prominent compared with the background frequency of the SOC level, but with the dramatic increase in the number of GLP-1 RAs used, psychiatric AEs remain a notable proportion of the overall AEs associated with GLP-1 RAs ( Table 1 )

The medication has exhibited minimal risk of hypoglycemia, a common concern with certain diabetes treatments

Exciting times lie ahead

Below, clinicians and researchers share insights on the neurological, behavioral, and emotional shifts they've observed and why many believe GLP-1s could play a meaningful role in addiction treatment and recovery support