soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm A emulation in Nature Medicine shows that treatment with and tirzepatide showed similar levels of benefit on in people at elevated cardiovascular risk with obesity and diabetes. Link Canadian Perspectives 2025 Whiteboard on
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Evidence also indicates that these drugs might lower the overall risk of cancer, with semaglutide significantly reducing the risk for various conditions
Sankaranarayanapillai M, Zhang N, Baggerly KA, Gelovani JG

DPP-4 is a ubiquitous cell membraneassociated serine protease expressed in many tissues, including the gut (17, 18)
Although GLP-1 agonists can help to effectively treat type 2 diabetes and obesity, they may not be suitable for everyone

March 21, 2026
