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Yes, patients with Hashimoto's thyroiditis can safely use GLP-1 receptor agonists (liraglutide, semaglutide, dulaglutide) for diabetes or obesity management,...

While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron

These medications work by curbing hunger, delaying stomach emptying, and controlling blood sugar levels

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For drugs with a narrow therapeutic index, other factors need to be monitored closely, including plasma drug levels, patients clinical outcomes, and laboratory markers

One key distinction she highlighted is that tirzepatide acts on two hormone pathways, GLP-1 and GIP, which may make it more effective for some people in terms of fat loss, metabolism, and insulin resistance