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The new study offered a clue as to why: Among those taking GLP-1 receptor agonists, those whose tumors had more GLP-1 receptors were less likely to have their cancer metastasize, the researchers said

By addressing these underlying metabolic disturbances, GLP-1 agonists may indirectly support more regular ovulatory cycles

Also, because GLP-1 drugs engage the brain's reward circuitry the same system that governs not just craving but everyday motivation prolonged use could, in theory, dampen motivational drive in some people

The authors also establish that GLP-1 agonists increase the risk of adverse gastrointestinal events, including diarrhoea and nausea in children, in line with their known side effects in adults

Am J Clin Exp Immunol

Although GLP-1Rs role is not fully understood or investigated in breast tissue when activated by different agonists, it may increase or decrease the progression of breast cancer [67, 68]