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They are equally effective when taken together in one pill (fixed-dose combination, FDC) as when they are administered separately in two doses

However, recent experimental data in mice evidenced that sDPP-4 levels were not associated with inflammation [63]

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First, this study was limited to a single dose and fasting conditions because we excluded the effect of diet and examined the direct effect of GLP-1RA

That raises the possibility that improving overall metabolic health may be a major part of what we are seeing.