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Discontinuation requires gradual dose reduction and transition to alternative weight management strategies to prevent rebound weight gain

For semaglutide, treatment was initiated at 0.25 mg once weekly and titrated every 4 weeks (0.25 mg 0.5 mg 1.0 mg) until the approved maintenance dose of 1.0 mg was achieved

But comfort has no bottom

Indian J Gastroenterol

Following the recommended dose escalation schedule reduces the likelihood of severe side effects

Most Wegovy-related headaches are mild to moderate and occur during the dose escalation phase, typically improving within 812 weeks as the body adapts to treatment