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Fernando lvarez Guisasola y Xavier Cos Claramunt
Activation of microglia in the trigeminal nucleus caudalis (TNC) contributes to this progression

Novo Nordisk has highlighted strong early uptake for its obesity pill in the US in early 2026 , framing oral semaglutide in obesity as part of its growth strategy beyond injectables
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GLP-1 receptor agonists (GLP-1 RAs) such as semaglutide and tirzepatide have rapidly become some of the most transformative therapies in modern medicine

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