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211215 Recently, GLP-1 action has additionally been expanded to potential regulation of autophagy in islet beta-cells: Exendin-4 induced autophagy in INS-1E cells and isolated human islets during chronic exposure to excess nutrients, by promotion of autophagosomal-lysosomal fusion

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doi: 10.1111/dom.14775

Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists
