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The standard preparation is 2 mL of bacteriostatic water added to a 10 mg vial, producing a solution with cagrilintide at 2.5 mg/mL and semaglutide at 2.5 mg/mL

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It is important that Compounded GLP-1 Medications are kept refrigerated

In addition to the direct impact on the proportion of gut bacteria, GLP-1RAs were found to upregulate tight junction proteins in the intestinal mucosa, which helps prevent the translocation of bacteria to the blood

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This makes bacteriostatic water the standard choice for multi-dose vials, as it allows the solution to be stored and used for several weeks after the initial mixing