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Histamine intolerance results from impaired histamine breakdown by diamine oxidase (DAO), causing symptoms such as headaches, flushing, and gastrointestinal disturbances

These are symptoms specific enough to hypothyroidism that their presence should prompt consideration of the diagnosis

Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB, Cui X, Briere DA, Cabrera O, Roell WC, Kuchibhotla U, Moyers JS, Benson CT, Gimeno RE, DAlessio DA, Haupt A

In some cases, the reduced appetite was initially attributed to nausea or abdominal pain, though the low appetite persisted once side effects wore off

doi: 10.1111/dom.12824

Your prescribers office initiates the call from the number on the denial letter