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Participants received either Orforglipron (12 mg or 36 mg) or oral semaglutide (7 mg or 14 mg) over 52 weeks

For example, in a study on 36 DM patients treated with BBR (500 mg three times daily) for 13 weeks, 34.5 % experienced flatulence, diarrhea, abdominal pain, or constipation [7]

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