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Whilst standard therapeutic doses of semaglutide or liraglutide are carefully calibrated through extensive clinical trials, microdosing involves using a fraction of these established dosesoften below licensed starting doses

Moreover, weight-based daily insulin requirements (a marker of insulin sensitivity) were also reduced with semaglutide (0.77 (0.35) U kg day 1 ) compared to placebo (0.64 (0.28) U kg day 1 , P = 0.002)

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Phase 2 trial data showed participants losing an average of 24.2% of body weight at the highest dose over 48 weeks

On June 26, US-based TikTok creator Jon Kluth, who has 226,500 followers, posted a four-week update about taking reta, telling followers they could use code Jon to purchase it
