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However, T2DM patients with a lower tolerability for GLP-1R agonists may prefer treatment with DPP-4 inhibitors for the management of hyperglycemia

Blueprint Medicines), has managed to obtain more than 70% market share in USA, and now has the entire ex-US market to itself given the withdrawal of pralsetinib from these markets [7,8]

Medications with narrow therapeutic windows like warfarin, cyclosporine, or certain antiarrhythmics may reach toxic levels when combined with berberine
