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For semaglutide, this strategy results in a pharmacokinetic half-life of approximately seven days, enabling once-weekly dosing [6]

In pancreatic -cells, the major bioactive hormone is glucagon that is formed by cleaved by Proprotein Convertase Subtilisin/Kexin Type 2 (PCSK2/PC2)

However, these drugs can have side effects and usually require injections

However, they are expensive, meaning everyone living with obesity may not have the chance to use them

However, this plan is *not* designed for individuals that have extremely limited mobility, cannot stand for extended periods of time, or have difficulties completing activities of daily living