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Distinct from bowel obstruction that involves a mechanical or functional blockage in the intestines which prevents the normal movement of digested products [29], PI is a functional issue affecting the muscles and nerves, mimicking the symptoms of intestinal obstruction even in the absence of any physical blockage [9], [30]

Furthermore, there have been reports of individuals with insulin-dependent diabetes discontinuing insulin injections after initiating these agents, leading to fatal outcomes (Table 1) [14]

The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis

They help you stay on track, adjust your plan when needed, and encourage you to keep going