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Historically, clinical care has responded to that surface

The LEADER trial with liraglutide and the REWIND trial with dulaglutide did not show significant increases in retinopathy complications, though differences in trial design, patient populations, baseline retinopathy prevalence, and rates of glycemic improvement may explain these discrepant findings

Cardiovasc Res 117(2):423434

doi: 10.1111/jnc.15521 24 RodeAKOBuusTBMrazVAl-JaberiFAHLopezDVFordSLet al

Its possible some of those holdouts were waiting for a more convenient option, without the hassle of a needle and Lilly is betting their new pill will make GLP-1s accessible for many of them

Semaglutide is a medication used for both the treatment of type 2 diabetes and for long-term weight management in adults with obesity