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They help curb appetite, slow gastric emptying, and reduce postprandial glucose spikes. Youve likely encountered names such as semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda). Early versions of these drugs required daily injection

B12, vitamin D, and electrolytes (potassium, magnesium) are most commonly depleted during semaglutide treatment due to reduced food intake and altered absorption

The following table summarizes key GI side effect patterns observed in registration trials and real-world reports

Benefits of Tirzepatide Many people find that losing weight feels easier on tirzepatide because they're no longer constantly thinking about food or fighting intense cravings throughout the day

Self-reported experience of hypoglycemia among adults with type 2 diabetes mellitus (Exhype) Diabetes Res Clin Pract

Many patients wonder whether these medications affect thyroid function, especially since thyroid disorders and obesity often co-occur