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SIRT1 can bind and retain GAPDH in the cytosol, but SIRT5 actives GAPDH via demalonylation, thereby elevating glycolytic flux

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If needed, unopened pens may be kept at room temperature up to 86F for maximum 21 days before use

Those impurities can interfere with receptor binding studies, skew dose-response curves, and produce confounding variables that undermine research validity