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Therefore, if GLP-1 RA treatment specifically increases the risk of pancreatitis in this vulnerable population, such an effect would likely remain undetected in randomized trials

For the subgroup analysis, the studies were classified based on whether the patients from the control group received either metformin or placebo

Taking Rybelsus with food or other medications: The most frequent mistake is not waiting the full 30 minutes after taking Rybelsus before consuming food, drinks other than water, or other oral medicines

Patients should inquire about their individualized treatment goals, including whether mucosal healing has been achieved, current inflammatory marker levels, and the appropriateness of their existing IBD regimen

For others, a single agonist like semaglutide may be more appropriate

In this retrospective, observational study, we analysed glycated haemoglobin (HbA1c) and weight following switching to semaglutide from any other GLP-1 RA, using US electronic health records and prescription data