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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Aitken TJ, Liu Z, Ly T, Shehata S, Sivakumar N, La Santa Medina N, et al

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Main text Modern GLP-1 receptor agonists and co-agonists (GLP-1 medicines) such as liraglutide, dulaglutide semaglutide, and the GLP-1R/glucose dependent insulinotropic polypeptide receptor (GIPR) co-agonist tirzepatide, were initially developed for the treatment of type 2 diabetes (T2D) due to their actions to increase insulin and decrease glucagon secretion and slow gastric emptying through effects on the pancreas and brain

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