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However, combining medication with modest lifestyle changes typically yields better, longer-lasting results

Random-effects models were applied, and sensitivity analyses examined result stability

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Rapid improvement in glucose control has been associated with a temporary worsening of diabetic retinopathy, but other mechanisms cannot be excluded

The high prevalence of comorbidities such as diabetes, visceral obesity, and aging, which contribute to systemic inflammation, plays a pivotal role in the pathogenesis and progression of HFpEF
