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In agreement, a 1.4-fold faster CL and a 1.6-fold shorter MRT were calculated for GLP-1 LX compared to GLP-1 WT with gPKPDSim (Supplementary Table 4)

Studies are exploring whether GLP-3 might enhance insulin sensitivity through mechanisms distinct from GLP-1s primary effects on insulin secretion, offer benefits for patients who dont respond optimally to GLP-1 agonists, provide complementary effects when used alongside other treatments, or address specific aspects of metabolic dysfunction in diabetes

Grateful to my mentors, co-authors, and the journal editorial team for their support throughout this journey

Brown, E., Wilding, J
