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Researchers in The Lancet highlight coronary arterial inflammation's role in increasing major adverse cardiac events and cardiovascular deaths, irrespective of coronary artery disease presence.

Combination strategies (GLP-1 + BAT activator) may preserve lean mass, enhance adherence, and amplify CV/metabolic benefits

Glucagon-like peptide-1 (GLP-1) is an incretin known for its anti-obesity effects, and several effective drugs targeting GLP-1 receptors (GLP-1Rs) have recently been developed to treat obesity

Alongside the anticipated CV safety of many of these agents, evidence for certain sodiumglucose transporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have revealed potential cardioprotective effects in patients with T2D who are at high risk of CVD events